Cost Saving

Save up to 79% of the cost of category C venlafaxine XL  prescriptions by prescribing Vencarm XL1*

By switching prescriptions of generic and brand originator venlafaxine prolonged-release 37.5mg, 75mg, 150mg and 225mg tablets and capsules to Vencarm XL, the average PCO could save £105,128 per year.***

Vencarm XL Cost Calculator

To find out how much you could save by prescribing Vencarm XL, please follow the instructions on the Vencarm XL calculator:

Vencarm XL is part of the cost-saving prolonged-release product range from Aspire Pharma.

  • Vencarm XL 37.5mg, 75mg, 150mg and 225mg capsules are the lowest priced Venlafaxine XL capsule range available with all 4 strengths3
  • Vencarm XL 37.5mg and 225mg capsules are lower in price than the venlafaxine XL capsule and tablet UK Drug Tariff price1
  • Savings of up to 79% on the current UK Drug Tariff price for venlafaxine 37.5mg and 225mg prolonged-release capsules and tablets1*
  • Vencarm XL has the same indications as the originator product, Efexor XL, (venlafaxine prolonged-release capsules) including General Anxiety Disorder and Social Anxiety Disorder.4,5
  • Patients treated with venlafaxine prolonged-release tablets may be switched to venlafaxine prolonged-release capsules at the equivalent daily dosage.6
  • Vencarm XL is bioequivalent to the originator EFEXOR XL (Venlafaxine Prolonged Release) Capsules7
  • Aspire Pharma offer a price and supply guarantee for this product.8**
  • Stocked in all mainline wholesalers

Table 1: Price of Vencarm XL capsules and venlafaxine XL tablets in the UK Drug Tariff

Vencarm XL Capsules (28)NHS List PriceVenlafaxine XL tablets Drug Tariff price equivalent to 28 tablets1Vencarm XL savings per packVencarm XL capsules % saving on price of tablets in Drug Tariff (28)1
37.5 mg capsules£3.30 37.5mg£6.16£2.8646%
75mg capsules£2.59 75mg£2.43-£0.16-7%
150mg capsules£3.89 150mg£3.64-£0.25-7%
225mg capsules£9.90225mg£31.36£21.4668%

Table 2: Price of Vencarm XL capsules and venlafaxine XL capsules in the UK Drug Tariff

Vencarm XL Capsules (28)NHS List PriceVenlafaxine XL capsules Drug Tariff price1Vencarm XL savings per packVencarm XL capsules % saving on price of capsules in Drug Tariff (28)1
37.5 mg capsules£3.30 37.5mg£5.25£1.9537%
75mg capsules£2.59 75mg£2.86£0.279%
150mg capsules£3.89 150mg£4.10£0.215%
225mg capsules£9.90225mg£47.11£37.2179%

*Based on up to 79% saving on the cost of Category C venlafaxine XL capsules and tablets in the UK Drug Tariff. **No change in price subject to no material change to the products or Category C of the UK Drug Tariff until the 2024 PPRS review. ***Savings based on market data in reference 2. Savings calculated from 2018 spend for 132 PCOs switching their generic and originator brand 37.5mg, 75mg, 150mg and 225mg venlafaxine prolonged-release tablets and capsules prescriptions to Vencarm XL.
1) July 2022 UK Drug Tariff. 2) Insypher GPPLPD Date Range: Aug-21 – Oct-21. 3) Dictionary of Medicines and Devices. Available at: (Accessed February 2022). 4) Vencarm XL (venlafaxine) capsules SmPCs. 5) Efexor XL (venlafaxine) capsules SmPCs (eMC – accessed February 2022). 6) BNF volume 78 September 2019 – February 2022. 7) Data on file, 1010067149 v 5.0 September 2021 . 8) 101008058 v 32.0 May 2022 Cost-saving Prolonged-release Range Supply guarantee Letter


For further information please call: 01730 231148,
email: or visit
Adverse events should be reported. Reporting forms and information can be found at
Adverse events should also be reported to Aspire Pharma Ltd on 01730 231148

For more information about Vencarm XL (venlafaxine), please see the abbreviated prescribing information.

Revision reference – Vencarm XL_10_27.07.2022

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