Vencarm® XL meets all the relevant regulatory requirements of a bioequivalent medicine (Reference product EFEXOR XL® (venlafaxine prolonged-release capsules) (Pfizer Limited, UK)).1 Bioequivalence studies of the 150 mg strengths (Fasting, Fed & Steady state [under fed conditions]) of the Test (venlafaxine XL) and Reference product (EFEXOR XL® (Pfizer Limited, UK)), were carried out comparing the mean plasma concentrations, for both Venlafaxine and the major metabolite, O-Desmethylvenlafaxine. The graphs for Venlafaxine are provided.
Single dose study comparing Vencarm XL 150mg and Efexor XL 150mg under fasted conditions
Single dose study comparing Vencarm XL 150mg and Efexor XL 150mg under fed conditions